ABOUT ENLIGHTEN SCIENTIFIC is a technical consultancy founded by me — John F. Miller — in early 2017. After 24-years of working in the pharmaceutical industry I decided to retire from the only company I had worked for — GlaxoSmithKline. I began my GSK career in 1993 working on the Read More

You say nano, I say…

You say nano, I say… Since the explosion of nanotechnology in the last couple of decades, the terminology used to describe a liquid dispersion has become very confused and contentious. The terms nanodispersion, nanoparticle dispersion, nanosuspension, colloidal dispersion, and colloid suspension are often used interchangeably or limited to rigid definitions, Read More

Next Generation ELS

  This is the presentation given by Enlighten Scientific owner John F Miller at the American Chemical Society National Meeting in Boston on 23 August 2018. It is the first public talk about Enlighten Scientific’s ground-breaking Next Generation Electrophoretic Light Scattering system (NG-ELS) that surpasses any available commercial instrument for Read More

Product Development

Product Development I have more than 24 years’ experience working in the pharmaceutical industry. Most of that time was concerned with liquid suspensions of micronized drug substances for delivery to the lung. Though this work included developing aqueous suspensions for nebulization and pressurized liquid carbon dioxide formulations, by far the Read More


Instrumentation I have significant knowledge and experience of conceiving and developing novel instruments for characterizing a range of subjects. For example, I invented Phase Analysis Light Scattering which has become the de facto method of measuring electrophoretic mobility and zeta potential of colloidal suspensions. This innovation pushed the resolving power Read More

Colloid Science

Colloid Science I gained my PhD in colloid chemistry in 1990 by inventing a method to determine very small electrophoretic mobilities of dispersions in non-polar media. I named the method Phase Analysis Light Scattering (PALS). Today, PALS is the de facto method to measure zeta potential of a wide variety Read More

Experimental Design

Experimental Design I have learned during my career that many experimental investigations were inefficient. These were accompanied by a poor understanding by the technical teams of the power of statistical analysis and a similar level of understanding by the statistical teams of the underlying physical basis of the experimental factors being studied. Read More