This video showcases the prototype of a Next Generation Electrophoretic Light Scattering instrument, proven to be capable of handling high conductivity samples with ionic strengths up to 6 molar, a range unachievable by commercial zeta potential instruments. I demonstrate its unique ability to perform electrophoretic light scattering using both a laser Doppler method and phase analysis light scattering, an innovation of my PhD research. The instrument operates at high electric field frequencies, displaying real-time voltage and current data, and effectively monitors and compensates for electrode polarization – a common issue in high conductivity zeta potential measurements. I highlight the instrument’s advanced features, such as its resistance to polarization even at nearly two molar ionic strength, and its immunity to heating effects during measurements. The instrument’s ability to provide accurate, reliable data is further demonstrated by its simultaneous measurement of phase function using the PALS method and the distribution method, with results from both methods closely matching. This groundbreaking instrument also measures the sample’s temperature directly, unlike commercial counterparts, ensuring more accurate readings. The video presents a breakthrough in electrophoretic light scattering technology, showcasing the instrument’s unparalleled capabilities in handling challenging samples.

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